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The Best CBD oil for inflammation

 CBD oil

CBD is a non-psychoactive molecule produced by cannabis plants. It is known to fight inflammation and, for this reason, could play an important role for athletes and patients.

The CBD is gaining ground as a medicinal compound, and as a nutritional and wellness supplement. In recent years this non-psychoactive cannabinoid has been thoroughly studied, showing impressive results in terms of its anticonvulsant, neuroprotective and antioxidant properties. This cannabinoid is also showing its effectiveness in reducing inflammation, a factor of pain and discomfort present in many conditions, and a contributing factor to several chronic diseases.



The CBD and the endocannabinoid system

The CBD occurs within the trichomes of cannabis plants, as a secondary metabolite. This molecule interacts with the human body in several ways, exerting its effects partially through serotonin and vanilloid receptors. Similar to other cannabinoids, CBD also influences the endocannabinoid system. This system is composed of cannabinoid receptors (CB1 and CB2), which are found in the cell membranes of many different cell types distributed throughout the body.

Several cannabinoids achieve their medicinal effects by joining these receptors. Although CBD does not bind directly to these receptors (in fact it is known to be an antagonist), it still indirectly influences the endocannabinoid system. CBD has the ability to increase or decrease the binding action of certain receptors, and also acts as an anandamide reuptake inhibitor. 
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What is inflammation?

Although it is often maligned and perceived negatively, inflammation is actually a vital physiological process and a fundamental aspect of our body's innate immune response. However, excessive inflammation is considered a contributing factor in chronic diseases, such as cancer or rheumatoid arthritis.

Acute or severe inflammation is usually the result of a traumatic injury, such as a sprained ankle or muscle contracture, and manifests through pain, redness, immobility, swelling and burning. This type of inflammation is a response that aims to protect the injured area and activate the healing process. Certain cells are directed to the affected area and begin to clean the remains and damaged tissues. Although anti-inflammatory drugs are often used to prevent this response and control pain, the body needs to go through this phase, so the use of these drugs could be considered controversial.

Chronic inflammation is defined as inflammation that persists for prolonged periods and may be caused by pathogens, viruses, and an overactive immune response. This type of inflammation can last from months to years and can occur when the immune system perceives healthy tissues as a threat and begins to attack them. This is known as an autoimmune disease. These conditions include asthma, rheumatoid arthritis, Crohn's disease and sinusitis.



The CBD and inflammation

CBD oil could have a therapeutic role in both types of inflammation. This cannabinoid has shown potential by helping to mediate the immune response associated with autoimmune diseases, such as those mentioned above, as well as neuropathic pain, hypertension, Alzheimer's disease and depression. A scientific article on this mechanism states that CBD is promising for the development of anti-inflammatory drugs. The molecule could act to combat the inflammation and oxidative stress associated with it in several ways, including by exerting an immunosuppressive effect on macrophage and microglial cells - cells that play a role in inflammation and immunity.

It has also been shown that CBD significantly reduces the pain of chronic inflammation, possibly by activating glycogen receptors.

After applying a CBD oil treatment to mice, there was a reduction in the levels of macrophages in the intestines of rodents, pointing to future therapeutic strategies with CBD for the treatment of intestinal inflammatory diseases

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